Julian Nagelsmann will reunite with Lewandowski at the Allianz Arena.
The Poland forward left Bayern Munich this summer ending his nine-year spell with the Bavarians.
He scored 344 times in 374 games for Bayern and signed for the Catalan giants this summer.
The veteran forward has already scored nine goals in six games for his new club.
“I am looking forward to it, not so much as an opponent because he’s very dangerous, but as a person I will be pleased to see him,” said Nagelsmann.
“I hope the fans will honour that too, regardless of how things were with his departure.”
“He is their most dangerous threat in front of goal,” added Nagelsmann. “If he maintains the physical fitness he can play for sure a few more seasons at this level.
“In the last few years he has been scoring about 40 goals a year. He is on a good road towards achieving that this season.
“We have to stop passes and crosses to him. But there are several other very good players in that team as well.”